Search results for "Retinal toxicity"

showing 2 items of 2 documents

What can visual caregivers expect with patients treated for SARS-CoV-2? An analysis of ongoing clinical trials and ocular side effects

2020

Within the COVID-19 pandemic context, the WHO has proposed a list of medicines to treat patients with severe acute respiratory syndrome (SARS-CoV-2). An analysis of their ocular side effects was performed. Only chloroquine and hydroxychloroquine were found to have an ocular impact in the medium and long-term. Detailed search strategies were performed in EMBASE, MEDLINE, SCOPUS and WOS Core Collection. Additionally, the worldwide ongoing clinical trials including chloroquine or hydroxychloroquine were evaluated, and their proposals of drug administration and exclusion criteria analyzed. In general, high maximum cumulative doses of chloroquine or hydroxychloroquine are being used for a short…

0301 basic medicinemedicine.medical_specialtyDrug-Related Side Effects and Adverse ReactionsCoronavirus disease 2019 (COVID-19)Health PersonnelRetinal pathology / researchSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Context (language use)medicine.disease_causeRetinaAntimalarials03 medical and health sciences0302 clinical medicineRetinal DiseasesChloroquineInternal medicinePandemicmedicineHumansRETINARetina – medical therapiesCoronavirusPharmacologyOphthalmologistsSARS-CoV-2business.industryCOVID-19ChloroquineHydroxychloroquineGeneral MedicineSystemic drug retinal ToxicityTechniques of retinal examinationCOVID-19 Drug TreatmentCoronavirusClinical trialOphthalmology030104 developmental biologyCaregiversMedicina Preventiva y Salud Pública030221 ophthalmology & optometryHuman medicinebusinessHydroxychloroquinemedicine.drugEuropean journal of ophthalmology
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Visual fields in a chloroquine treatment

2014

Purpose: In this study, we describe contrast sensitivity losses in the visual field of a patient affected by chloroquine toxicity, measured with stimuli favoring different visual mechanisms. We have compared these results with those of other, usual clinical tests. Methods: The vision of a patient who underwent ten years of chloroquine treatment was analyzed by a battery of clinical tests: visual acuity (VA), Amsler’s grid, Farnsworth–Munsell 100-hue test, spectral domain optical coherence tomography, multifocal electroretinogram (ERG), white-on-white and red-on-white Humphrey perimetries, chromatic and achromatic contrast sensitivity perimetry tests, and fluorescein angiography. Measurement…

genetic structuresColor visionRetinal damageColor perceptionChloroquineÒpticaRetinal damageVisual fieldRetinaeye diseasesSensory SystemsVisual fieldOphthalmologyGeographyRetinal toxicityRetinal toxicityOptometryVisióCartographyÓpticaClinical Optometry
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